How does AI increase the efficiency of screening drugs by 10 times? On June 18, HUAWEI CLOUD and Shanghai Institute of Medicine of Chinese Academy of Sciences solved the mystery
Abstract: On June 18th, the Huawei Cloud TechWave Global Technology Summit (Artificial Intelligence & Data) will focus on hot topics such as artificial intelligence, big data, database, and Huawei Cloud Stack, and join hands with IT elites, technology experts, and pioneers from all over the world. , Partners talk about cutting-edge technology
Drug R&D is a long process. Traditional drug R&D requires a large number of R&D personnel, which takes ten to fifteen years and billions of dollars in R&D funding. In recent years, technological changes in the field of drug research and development have benefited from the development of new technologies such as cryo-electron microscopy, DNA-encoded compound libraries, and various omics technologies. The field of drug research and development generates massive amounts of data, and AI technology can dig deeper into these data, so the integration of IT and BT may become a new paradigm for new drug research and development.
For example, in the early stage of the new crown epidemic in 2020, Academician Jiang Hualiang of the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences, Shanghai University of Science and Technology and Wuhan Institute of Virology established a joint research team to analyze the world's first high-resolution Mpro protein structure in just a dozen days. , And was released in the first time, which greatly promoted the research and development of antiviral drugs, and related results were published in Nature and Science magazines.
On June 18th, the Huawei Cloud TechWave Global Technology Summit (Artificial Intelligence & Data) was held in Shanghai. Dr. Mingyue Zheng, a researcher at the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, will publish the theme of "New Coronary Epidemic Every second must be determined, AI improves screening efficiency by 10 times" The speech introduced the current challenges and key issues facing drug screening, the latest progress in the field of AI drug research and development, and demonstrated the whole process of "cloud + AI" end-to-end empowerment drug screening.
At the meeting, researcher Zheng Mingyue will introduce multiple AI drug research and development cooperation projects based on HUAWEI CLOUD's medical agent EIHealth carried out with the HUAWEI CLOUD team, such as the iPhord algorithm for predicting protein structure from the primary sequence for early drug target research. Relocate the AI prediction algorithm, use the multi-omics automatic modeling tool AutoOmics to quickly discover biomarkers, use the personalized federated learning integration algorithm FedAMP to achieve efficient and safe integration of pharmaceutical enterprise data, and use Huawei Cloud's automatic AI modeling tool for omics data AutoGenome accurately predicts drug properties, etc.
It is understood that the large-scale virtual drug screening cloud service developed by Shanghai Pharmaceuticals of the Chinese Academy of Sciences and the Huawei Cloud team uses the super computing power of Huawei's cloud million cores to achieve a tenfold increase in drug screening efficiency; the original iFitDock algorithm is built in the service to achieve rigidity at the same time With flexible docking, it truly reflects the physiological state and function of the protein; the service provides a billion-scale, largest synthetic drug library DrugSpaceX drug screening library, which can trace the reaction path and quickly realize drug generation. This service can provide better services for pharmaceutical companies and scientific research units, and facilitate the research and development of new drugs.
For more progress on AI large-scale drug screening services, please follow the Huawei Cloud TechWave Global Technology Summit (Artificial Intelligence & Data).
On June 18, the Huawei Cloud TechWave Global Technology Summit (Artificial Intelligence & Data) focused on hot topics such as artificial intelligence, big data, databases, and Huawei Cloud Stack, and joined hands with IT elites, technology experts, pioneers, and partners from all over the world. Talk about cutting-edge technologies, release the latest Huawei Cloud products and solutions, share industry best application practices, and discuss the growth path of enterprise intelligent upgrades. Innovative and inclusive, go all the way. Click to view 【Event Details】